The short answer: Most people notice less hunger within the first few weeks, but the scale moves slowly at first because the starting dose is only a first step. In the largest Zepbound (tirzepatide) trial, average weight loss reached roughly 15% to 22% of body weight at 72 weeks, depending on the dose, and it
If you’re considering Zepbound (tirzepatide) for weight management, understanding its potential side effects is essential for making an informed decision. This FDA-approved medication has helped many patients achieve significant weight loss, but like all medications, it comes with considerations you should discuss with your healthcare provider. At BeLite Medical Center, we believe informed patients are
In May 2025, the New England Journal of Medicine published the first head-to-head clinical trial comparing two of the most effective anti-obesity medications on the market: tirzepatide (Zepbound) and semaglutide (Wegovy). This was the phase 3b open label extension of the SURMOUNT-5 clinical trial involving 751 non-diabetic obese patients. The main finding was that tirzepatide led to significantly more weight loss than semaglutide over 72
In May 2025, the New England Journal of Medicine published the first head-to-head clinical trial comparing two of the most effective anti-obesity medications on the market: tirzepatide (Zepbound) and semaglutide (Wegovy). This was the phase 3b open label extension of the SURMOUNT-5 clinical trial involving 751 non-diabetic obese patients. The main finding was that tirzepatide led to significantly more weight loss than semaglutide over 72
In the ever evolving field of weight management, two recently marketed drugs have captured significant attention: Wegovy (semaglutide) and Zepbound (tirzepatide). While originally designed to address type 2 diabetes, both medications demonstrated impressive results in overweight individuals who do not have type 2 diabetes. This post will explore what current clinical trial data tells us
Updated December 2025 At Belite Medical Center, we understand that sustainable weight loss is not just about discipline—it’s about biology. Hormones, genetics, appetite signaling, sleep, stress, and metabolism all play a role in body weight. For many patients, lifestyle strategies alone aren’t enough, and that’s where today’s weight-loss medications can be transformative. Modern anti-obesity medications
