Purpose This document summarizes PubMed-indexed clinical evidence on the safety and efficacy of longer-term phentermine monotherapy, with emphasis on cardiovascular risk, blood pressure, heart rate, valvular disease, pulmonary arterial hypertension, addiction potential, metabolic benefits, and weight loss outcomes. Regulatory Context Phentermine is FDA-approved for short-term use (typically defined as up to 12 weeks). Prescribing beyond
Many patients considering phentermine for weight loss have questions about safety, side effects, and how long it can be used. Below is a clear, evidence-based overview written for patients, based on published medical research and clinical practice at BeLite Medical Center. What Is Phentermine? Phentermine is a prescription medication that reduces appetite by acting on